Background: Globally and nationally, infant mortality occurs predominantly during the neonatal period. WHO reported that in 2024, there were 4.9 million deaths among children under five years of age, with 2.3 million occurring during the neonatal period. Breast milk is the best food for infants because it contains nutrients and antibodies. In the working area of Pandak I Public Health Center, the coverage of exclusive breastfeeding in 2025 was 81.40% among infants aged 0–5 months, but decreased to 60.09% at 6 months of age. Improper breastfeeding techniques may hinder the breastfeeding process; therefore, mothers’ knowledge of breastfeeding techniques is one of the factors that supports the success of exclusive breastfeeding. Objective: To determine the relationship between mothers’ knowledge level of breastfeeding techniques and the success of exclusive breastfeeding among infants aged 6–12 months at UPTD Pandak I Public Health Center in 2026. Methods: This quantitative study used an analytical observational design with a cross-sectional approach. The sample consisted of 30 respondents selected using purposive sampling. Data were collected using a questionnaire and analyzed using the Chi-Square test. Results: Of the 30 respondents, the majority had a high level of knowledge about breastfeeding techniques, consisting of 20 respondents (66.7%), while 10 respondents (33.3%) had a moderate level of knowledge. The majority of respondents successfully provided exclusive breastfeeding, consisting of 21 respondents (70.0%), while 9 respondents (30.0%) did not successfully provide exclusive breastfeeding. The Chi-Square test showed a significant relationship between mothers’ knowledge level of breastfeeding techniques and the success of exclusive breastfeeding, with a p-value of 0.000 (p<0.05). Conclusion: There is a relationship between mothers’ knowledge level of breastfeeding techniques and the success of exclusive breastfeeding among infants aged 6–12 months at UPTD Pandak I Public Health Center in 2026.